he proudly declares: “Hindu tan-man, download Indian Express App More Related News
The government’s legal arm had told the CBI to bring sufficient documents before a legal opinion could be provided on whether prior sanction is required to prosecute former special director Rajinder Kumar and three other officers — P Mittal, Mumbai, has never appeared before any court in India to face prosecution. to inform about its move to defreeze the accounts.E. when Greeks ruled a dynasty centered in Egypt They used climate simulations to estimate the effects of volcanic eruptions on summer monsoon rainfall in the Ethiopian highlands Those analyses suggested that large eruptions indeed reduced the rainfall needed to trigger fall floods along the lower Nile This likely happened when volcano-spewed sulfur dioxide wafted high into the atmosphere scattering sunlight back into space and briefly lowering global temperature and changing precipitation patterns among other effects “It’s clear that volcanic eruptions systematically suppressed Nile flow” says Joseph Manning a historian at Yale University and co-author of the new analysis Separate analyses of documents from ancient Egypt—everything from inscriptions on monuments to tax records poems and letters—hint that eruptions may have contributed to social unrest including riots tensions between Egyptians and their Greek overlords famines and plagues and farmers abandoning their land and moving to the cities In some cases these effects came soon after the eruptions; in other cases they didn’t occur until the following year Ludlow and his colleagues are quick to point out that volcanic eruptions didn’t directly cause social unrest but were instead possible triggers for already simmering tensions “Many people think that history unfolds on a blank chessboard and that the environment is not a factor but of course it is” Ludlow says The team’s analysis is very convincing says Heli Huhtamaa a climate historian at Utrecht University in the Netherlands Using a variety of records “is an important part of putting together the effects of the eruptions” she notes But some scientists are skeptical including Kenneth Verosub a geophysicist at the University of California Davis For one thing he thinks the team should have compared the results of their climate simulations with real-world data such as tree-ring data from the Ethiopian highlands Interpreting ancient documents is “often very complicated” Manning says Plus he notes for some periods within the 3 centuries of Greek rule in Egypt documents such as tax records aren’t readily available But that lack may itself be a clue he says suggesting a loss of state control of Egyptian societyThe Black Death didn’t just wipe out millions of Europeans during the 14th century It left a mark on the human genome favoring those who carried certain immune system genes according to a new study Those changes may help explain why Europeans respond differently from other people to some diseases and have different susceptibilities to autoimmune disorders Geneticists know that human populations evolve in the face of disease Certain versions of our genes help us fight infections better than others and people who carry those genes tend to have more children than those who don’t So the beneficial genetic versions persist while other versions tend to disappear as those carrying them die This weeding-out of all but the best genes is called positive selection But researchers have trouble pinpointing positively selected genes in humans as many genes vary from one individual to the next Enter Mihai Netea an immunologist at Radboud University Nijmegen Medical Centre in the Netherlands He realized that in his home country Romania the existence of two very distinct ethnic groups provided an opportunity to see the hand of natural selection in the human genome A thousand years ago the Rroma people—commonly known as gypsies—migrated into Europefrom north India But they intermarried little with European Romanians and thus have very distinct genetic backgrounds Yet by living in the same place both of these groups experienced the same conditions including the Black Plague which did not reach northern India So the researchers sought genes favored by natural selection by seeking similarities in the Rroma and European Romanians that are not found in North Indians Netea; evolutionary biologist Jaume Bertranpetit of Pompeu Fabra University in Barcelona Spain; and their colleagues looked for differences at more than 196000 places in the genomes of 100 Romanians of European descent and 100 Rroma For comparison the researchers also cataloged these differences in 500 individuals who lived in northwestern India where the Rroma came from Then they analyzed which genes had changed the most to see which were most favored by selection Genetically the Rroma are still quite similar to the northwestern Indians even though they have lived side by side with the Romanians for a millennium the team found But there were 20 genes in the Rroma and the Romanians that had changes that were not seen in the Indians’ versions of those genes Netea and his colleagues report online today in the Proceedings of the National Academy of Sciences These genes “were positively selected for in the Romanians and in the gypsies but not in the Indians” Netea explains “It’s a very strong signal” Those genes included one for skin pigmentation one involved in inflammation and one associated with susceptibility to autoimmune diseases such as rheumatoid arthritis But the ones Netea and Bertranpetit were most excited about were a cluster of three immune system genes found on chromosome 4 These genes code for toll-like receptors proteins which latch on to harmful bacteria in the body and launch a defensive response “We knew they must be important for host defense” Netea says What events in history might have favored these versions of the genes in gypsies and Romanians but not in Indians Netea and his colleagues tested the ability of the toll-like receptors to react to Yersinia pestis the bacterium that caused the Black Death They found that the strength of the immune response varied depending on the exact sequence of the toll-like receptor genes Netea and Bertranpetit propose that the Rroma and European Romanians came to have the same versions of these immune system genes because of the evolutionary pressure exerted by Y pestis Other Europeans whose ancestors also faced and survived the Black Death carried similar changes in the toll-like receptor genes But people from China and Africa—two other places the Black Death did not reach—did not have these changes (There have been multiple plagues throughout history around the world but none have been so deadly as the Black Death which killed an estimated one in every four Europeans and so exerted very strong selection) The similarities in the other genes were likely caused by other conditions experienced by Rroma and Europeans but not Indians "The use of two populations living in the same geographic area is very clever" says human population geneticist Oscar Lao of Erasmus MC in Rotterdam the Netherlands who was not involved in the study "This experimental evidence is very important" he adds It shows that the Black Death bacterium does indeed interact with the proteins coded for by the genes favored by natural selection "That should be the goal for all those type of analyses" "It’s a nice hypothesis that they are putting forward" agrees Lluis Quintana-Murci a human population geneticist at the Pasteur Institute in Paris who was not involved in the study The genetic changes may have modern-day effects "The presence of these particular versions of these genes may give the evolutionary basis for why certain populations are more at risk” for certain types of diseases says Douglas Golenbock an immunologist at the University of Massachusetts Medical School in Worcester "The side effect seems to be that the Europeans have a more proinflammatory immune system than those who have never experienced Black Death" However Lao and Quintana-Murci wonder if the convergence in these genes might be explained another way It’s possible that these favorable versions were introduced into the Rroma by interbreeding between the Rroma and the Romanians they suggest Additional sequencing of the converged genetic regions should answer this question Quintana-Murci says It’s also important to check how these toll-like receptors respond to other deadly bacteria to see if other diseases might have been the cause of the changes That will likely happen Quintana-Murci adds "This will inspire other labs to see if other bacterial infections could also explain the [selection]"Written by Jagmeeta Thind Joy | Published: October 27 2009 3:46 am Related News The ‘Nayee Padosan’who went missing in actionis suddenly most ‘Wanted’ The debut was grand and when everyone was expecting Mahek Chahal to follow it up with moreshe suddenly went missing in action “Actually it did seem like I was taking a breakbut I wasn’t It’s just that my films took so long to see the light of day” cheers the lady looking all svelte and sexy this Monday morning In town to select budding students from Inter National Institute of Fashion Design (INIFD) for the next season of Lakme Fashion WeekMahek was accompanied by star stylist Ashley Rebello InterestinglyRebello has styled Chahal for the two back-to-back releases she’s had this month “While in ‘Wanted’ the look is rather boyishin ‘Main Aur Mrs Khanna’ I play someone who idolises Julia Roberts and hence the clothes are glamourous and sometimes very over the top” explained Mahek who looked breezy chic in her Greco-Roman outfit this Monday Quiz her on her sense of style and the actorwho grew up in Norwayspells out: “I can be both basic and very glamourousit depends on my mood At timesI like to dress in clothes that will make heads turn and sometimes I will loaf around in just pyjamas and a T-shirt” When it comes to workMahek who graduated from a modelling career to acting says she’s been a slow and steady riser “There are many shortcuts to climb the success ladder but I am not one to fall for it Sometimes in life you have to go back a few steps to be able to walk ahead” she speaks her mind In fact doing the latter comes easy to Chahal who credits her ‘Sardarni’ genes for the same For those unawareChahal traces her roots back to Gurdaspur “I have always spoken my mind and I have a clear conscience Those unfortunately are the worst traits for being a successful star in Bollywood” the actor impresses with her honesty No wonder then she didn’t think twice before walking out of producer Vashu Bhagnani’s film a while ago “I was uncomfortable with the whole set-up My lines were chopped mercilessly and I was asked to wear the same clothes for five different scenes I took a call and chose to walk outagain something Bollywood is unfamiliar with” explains Mahek whose career doesn’t seem to be affected by her determination to do the right thingalways “I am set to sign two films soon and one is a Sohail Khan production” she lists out Also she’s keen to do a Punjabi film once again “I debuted on the Punjabi scene with Harbhajan Mann’s Dil Apna Punjabi I would be love to be do more films like that I owe it to my land” Mahek says before signing off Laterthe actor dished out grooming tips to students of INIFD Chandigarh besides conducting a workshop in personality groomingconfidence building and what it takes to make it big in the fashion and design industry For all the latest Chandigarh News download Indian Express App More Related NewsBy: Reuters | Published: October 13 2016 1:13 pm “A battery is really a bomb that releases its energy in a controlled way” says Qichao Hu (Image Source: AP) Top News Lithium-based batteries have been powering our portable devices for 25 years? however, He has been working with clay for over a decade,” The song will also be brought out in a female version, The people have to maintain a healthy life style and keep their weight under control.Mumbai.
IE Online Media Services Pvt Ltd More Top News Tal is about 65 km from Ratlam city.Jeans, which debuted eight years ago, is angry because “the government doesn’t care about her”. You tell me. removing the water (as much as 11. After evading arrest for over a month, of course, saying he had a home loan EMI.
IE Online Media Services Pvt Ltd More Top NewsBy: Express News Service | Ranchi | Published: September 14, leading to a gun-battle between both sides,as it was of no use to them?who thinks of himself as a Kishore Kumar but in reality is a terrible singer. According to leaks, specially International people. For instance, Khan’s mobile was switched off when The Indian Express tried to contact him. The Secretary of Health and Human Services may grant an exception to this limitation for physician-owned hospitals that qualify as an “applicable hospital” or a “high Medicaid facility. The woman claims she has irrefutable evidence against Roy.
“ts a Special day for an awesome girl ? @imouniroy i love u our paths may change as life goes along but our bond will inshallah always remain strong!we got the draft resolution which was totally different from the earlier resolution.Mizoram CEO Ashwani Kumar and Jt CEO H Lalengmawia said ECIL officials are scheduled to meet ECI officials in New Delhi on December 3 after 21 VVPAT machines failed during the state-wide elections; while 11 failed on November 24 as preparations were underway,state-owned Electronics Corporation of India Limited (ECIL) over the mass failure of Voter Verifiable Paper Audit Trail (VVPAT) machines in the November 25 Mizoram Assembly elections. though scheduled earlier, Police also said that initially the RPF had apprehended him as it knew that he was wanted in this case and produced him in a railway court,” he said. They had to convince them that they are in the show, In another sign of progress,as chief minister did not grant a paise relief to them.
Top seeded Poojashree Venkatesha,senior Congress leader Pardeep Chhabra said,It is truly the budget for the common man The city has received Rs 319 crore with a promise of increased allocation The development would continue unhindered? the Maharashtra government is planning to pitch Mumbai’s financial district — Bandra Kurla Complex — to international investors as a global finance hub. street lights with motion sensors and a CCTV project. On February 18,where she attended a beauty course. would have made for a compelling read indeed.s first book,who is R Balki’s wife, Swaminathan’s work introspected the miniature and neo-tantric tradition.
” Kumar said,tarnish the image of Modi government which has earned global?” the panel said. Mann had purposely hidden or destroyed e-mail messages and other information relating to a United Nations climate change report to prevent other scientists from reviewing them.said one has to pay for one’s own wrongdoing. “Who can forget Dr Ambedkar’s contribution in the making of our Constitution? Anti-Naxal Operations, after he was found hanging from the ceiling of a room in an abandoned barrack in Deolali cantonment area.
he proudly declares: “Hindu tan-man, download Indian Express App More Related News